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Carlos Santana leading off Friday for Cleveland

Cleveland Indians first baseman Carlos Santana is batting atop the order for Friday's game at the Chicago White Sox.

What It Means:

Santana had been hitting sixth, but with Bradley Zimmer sitting against a lefty, Santana is back in the leadoff spot.

The Indians boast the slate's second-highest implied total at 5.69 for their clash with White Sox southpaw Derek Holland. Against righties, Holland is surrendering a .393 wOBA, 40.9% hard-hit rate and 43.8% fly-ball rate. Santana's .327 wOBA this season is a career-worst clip, and his wOBA against lefties is .308.