This article is geared towards FanDuel's main slate, which begins at 2:45 p.m. EST Wednesday and features six matches. The slate features nine of the top-10 clubs and the marquee match sees Chelsea host Tottenham, with the Blues a +125 favorite on FanDuel’s sportsbook, putting their implied win probability at 44.4%.

As with any DFS sport, it is imperative to have your players, especially the high-priced studs, live up to their price tag. When investing in any player, it is important to determine who will likely contribute in FanDuel's emphasized areas (goals, assists, and shots on target). It's also just as crucial not to overspend on players in bad matchups.

We should try to take advantage of the teams -- and players -- who play especially well either home or away, while also looking at oddsmakers' favorites and over/under totals. With a few clubs playing midweek matches, DFS players, as always, should check out injury reports and confirmed starting XI's when they become available since some players may be rested.

Let's take a look at three players across the pitch who should be avoided.