Los Angeles Chargers wide receiver Keenan Allen (heel) is not practicing on Wednesday for Week 16 versus the Buffalo Bills.

Los Angeles Chargers wide receiver Jalen Guyton (groin) was limited at practice on Wednesday for Week 12 against the Baltimore Ravens.

What should you know about every main-slate game in Week 17?

What should you know about every main-slate game in Week 16?

What should you know about every main-slate game in Week 15?

Murray is seeing decent volume and has a sweet home matchup with the Colts in Week 15. Which other usage trends do you need to know?

What should you know about every main-slate game in Week 14?

What should you know about every main-slate game in Week 13?

The Rams' offense has sputtered mightily of late, but a matchup with the Cardinals could revive Todd Gurley and company. Which other situations should we monitor on the Week 13 main slate?

What should you know about every main-slate game in Week 12?