San Francisco 49ers wide receiver Deebo Samuel (hamstring) will not play Week 10 against the New Orleans Saints on Sunday.
Samuel hasn't played since Week 7. Brandon Aiyuk caught 8 passes on 10 targets for 91 yards and a touchdown in Week 8 with Samuel sidelined before missing last game due to COVID-19 concerns. Richie James is expected to join Aiyuk and Kendrick Bourne in the 49ers' wide receiver rotation after he erupted for 9 catches on 13 targets with 184 yards and a touchdown last Thursday night.
Aiyuk is the top-ranked 49ers wide receiver in numberFire's Week 10 fantasy rankings. Our models project him for 6.4 targets and 10.0 FanDuel points. The first-round pick has a salary of $6,500 on the main slate. The Saints own the No. 10 pass defense in the league, per numberFire's advanced team rankings.