Carolina Panthers running back Christian McCaffrey (ankle) is expected to miss "multiple weeks," reports ESPN's Adam Schefter.
McCaffrey injured his ankle during the Panthers' Week 2 loss to the Tampa Bay Buccaneers on Sunday. Mike Davis stepped in as McCaffrey's replacement and hauled in 8 catches on 8 targets for 74 yards. Trenton Cannon could also be involved, but Davis is expected to be the Panthers' main back in Week 3 against the Los Angeles Chargers.
McCaffrey scored 22.8 FanDuel points with 59 rushing yards, 29 receiving yards, 4 catches (5 targets), and 2 touchdowns in Week 2. The Panthers will play a Chargers defense in Week 3 that currently ranks 14th against the run, per numberFire's advanced metrics.
Source: Adam Schefter, ESPN