Marlon Mack (ankle) sidelined Wednesday for Colts

Indianapolis Colts running back Marlon Mack (ankle) was held out of Wednesday's practice.

What It Means:

Mack is dealing with an ankle injury he suffered late in the Colts' Week 4 loss to the Oakland Raiders. It's supposedly minor, but if he's ruled out for Week 5, Jordan Wilkins and Nyheim Hines will split backfield duties.

The Colts face a Chiefs defense in Week 5 that is allowing the most rushing yards per carry (5.9) and second-most rushing yards per game (149.8).