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Daily Fantasy Football Week 16 Optimized Lineups
Colin Kaepernick will face the worst pass defense in the NFL this weekend.

If you had DraftKings Optimized Lineup

PlayerLineup SlotProjected FPCost
Peyton ManningQB27.74$9,300
LeSean McCoyRB31.59$8,500
Giovani BernardRB17.45$5,000
Calvin JohnsonWR24.16$9,000
Michael CrabtreeWR13.66$4,300
Golden TateFLEX13.80$4,000
Charles ClayTE11.26$3,900
Detroit LionsD/ST10.70$3,000
Mike NugentK9.09$3,000

DraftStreet Optimized Lineup

PlayerLineup SlotProjected FPCost
Colin KaepernickQB22.08$14,067
Philip RiversQB23.29$13,189
Jamaal CharlesRB22.39$17,181
LeSean McCoyRB26.52$15,554
Denarius MooreWR10.18$5,125
Donnie AveryWR7.91$3,632
Jared CookTE7.66$4,281
Matt ForteFLEX18.64$13,704
Giovani BernardFLEX15.91$10,337
New England PatriotsD/ST7.58$2,494

FanDuel Optimized Lineup

PlayerLineup SlotProjected FPCost
Philip RiversQB23.15$8,600
LeSean McCoyRB26.44$9,700
Giovani BernardRB15.71$6,700
A.J. GreenWR16.84$8,600
Julian EdelmanWR13.57$6,700
Golden TateWR10.91$4,700
Antonio GatesTE8.63$4,500
Tennessee TitansD/ST10.40$5,500
Mike NugentK9.09$5,000

Fantasy Feud Optimized Lineup

PlayerLineup SlotProjected FPCost
Peyton ManningQB23.98$186,000
Colin KaepernickQB21.32$145,200
Jamaal CharlesRB22.31$161,300
LeSean McCoyRB26.44$157,400
Golden TateWR10.91$63,100
Mike BrownWR8.77$34,800
Antonio GatesTE8.63$67,000
Giovani BernardFLEX15.71$98,200
Dennis JohnsonFLEX9.01$30,000
Tennessee TitansD/ST10.88$52,300

StarStreet Optimized Lineup

PlayerLineup SlotProjected FPCost
Colin KaepernickQB21.34$12,700
Philip RiversQB22.53$11,700
Jamaal CharlesRB24.69$14,500
LeSean McCoyRB28.51$13,500
Hakeem NicksWR12.66$8,400
Golden TateWR13.76$9,500
Vernon DavisTE13.60$10,400
Matt ForteFLEX21.22$13,200
Dennis JohnsonFLEX10.79$6,000

Week 16 Trends

The theme of Week 16: Stud running backs, cheap wide receivers. We've got our buddies LeSean McCoy and Jamaal Charles littered throughout each lineup, as both have nice matchups against the Bears and Colts, respectively. McCoy's matchup is especially delightful, as the Bears have the worst rush defense in the entire league according to our metrics. He could be the one to produce Week 15 Jamaal Charles numbers in Week 16.

To go along with these runners, a few of the optimized rosters have running back Giovani Bernard. Despite a lackluster performance against Pittsburgh last week, Bernard will face a Minnesota rush defense that's allowed the sixth-most fantasy points to opposing running backs, including the second-most running back receptions. Bernard's a pass-catching back, and should be able to find some holes in the defense.

Common names at quarterback are Philip Rivers and Colin Kaepernick. Rivers will face the same Oakland defense that's been getting torched by quarterbacks, as they've allowed at least one passing touchdown (seven to Nick Foles) in every game since Week 8. If you watched them against the Chiefs, you know they're not a strong unit.

Kaepernick provides a very high ceiling against Atlanta, numberFire's worst statistical pass defense in the NFL. The Falcons, outside of their game against Matt Flynn, have allowed two touchdowns (total) to every quarterback they've faced this year, including a three-score one to Kirk Cousins just a week ago.

Remember to use our projections to help sort out any confusion, or ask in the questions area of the site. And, as always, check back Sunday for updated rosters.

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