Week 5 brought with it a slew of injuries to big name players, perhaps none more notable than the broken ankle suffered by Odell Beckham that will likely sideline him for the rest of the season.

With the injuries piling up and bye weeks now appearing on the schedule, working the waiver wire becomes even more important -- we're not only looking for breakout players, but also for those steadily producing players that we can plug-and-play when on a bye week crunch.

Entering Week 6, our top options on the waiver wire include some top-notch running back handcuffs, wide receivers seeing more volume due to injuries, and a couple of streaming options at quarterback, tight end, and defense.

Here are 10 players to target on your waiver wire heading into Week 6.